I always thought doing a color themed town would be cool.
i.e. a Purple town would have Queenie, Bob, Becky, Mallary, Gigi, Sydney, Rod, Phil, Renee, and Static. There's more you could use too, such as Gloria, Diva (shudders), Sylvia, Fuchsia, etc...Purple flowers everywhere, town name and resident names shades of purple i.e. Wisteria, Thistle, Mauve, Plum...
Green: Mint, Charlise, Drago, Jitters, Frank, Celia, Henry, Lyman, Nibbles, and Opal with a lot of trees and shrubbery. Town names/resident names: Forest, Pine, Jungle, Fern, Teal...
Yellow: Eloise, Twiggy, Coach, Egbert, Tammy, Lopez, Goldie, Joey, Mira, and Clyde. Lemon, Mustard, Amber, Vanilla...
Pink could be Marina, Nana, Merengue, Peaches, Flora, Midge, Miranda, Vladmir, Pinky, Gayle, Puddles, Marcie, Peanut, Curly, Gala, Chrissy, Cookie, Peanut, Claudia, and/or Freya. Wow, there's a lot of pink villagers! Pink flowers, town name and residents names shades of pink i.e. Coral, Orchid, Rose, Barbie (barbie pink!), Cerise....
OR A RAINBOW TOWN! Pietro for the rainbow, Cheri for red, Biskit for Orange, Mira for yellow, Mint for green, Ed for blue, Queenie for purple, Vladmir for pink, Kiki for black, and Cranston for white.
I've also liked the idea of a flower themed town. Villagers would be:
-Flora, because of her name ofc.
-Rosie, Daisy, Poppy, and Lily- Flower names
-Gala who has flowers in her hair
-Willow is technically a tree but could work
-Tia: Flower on her cheek
-Hazel: Japanese name is Iris, a flower
No idea who the other one would be. Human residents named: Blossom, Azalea, Clover, and Ivy. Town name: Petalbay or something.
And kind of personal to me, a town themed around my AC:GC town with villagers from my GC town!
-All my starters: Bob, Bluebear, Pippy, Deena, Ed, Apollo
-Cupcake is no longer in the game, so Yuka was my second snooty to move in
-Kiki and Ribbot, my two faves who have been in all my towns ever
-Dora or Friga for the last one: Both have been in my GC town for quite some time
Ahhhhh I keep editing this because I keep thinking of more!
Alice in Wonderland themed town!
-Alice, obviously
-O'Hare, the Mad Hatter
-Moe, the Cheshire Cat
-Ruby, the White Rabbit
-Bonbon or Cole as March Hare
-Tweedledum and Tweedledee could be Francine and Chrissy, Ed and Julian, or Big Top and Kid Cat
-Queenie as the Queen of Hearts (put her in a heart shirt obviously)
-A mouse of your choice as the Dormouse, I would choose Samson myself