Games you wish you could play for the first time again?

The Legend of Zelda Phantom hourglass/Spirit Tracks ~ I was drawn into both of these games when I first played them. It was fun discovering I could throw chickens into the ocean too.
Also Lux Pain, as I loved the storyline/plot to it.
 
Rune Factory 4~ Out of nowhere I got this game and it was super fun and I was like addicted to it and it was during my visit to Virginia and I even got my little brother to get it the only problem is once you beat the main story and get married and have a kid it gets pretty boring but just playing through the game as a first timer again would be fun :)

Did you even beat the Arc 3? :U
 
Mass Effect seconded; the trilogy was one of my first western RPGs so I wasn't prepared for how attached I got to the writing and dialogue (and the choices, oh the choices). Probably Mass Effect 3 more than the others (yes, ending and all) because I went on a completely blind run at first, and by the time I started ME3 I had made some... not-so-optimal choices in the previous games (couldn't convince the quarians of Tali's innocence, for one). I lost a lot of my favorite characters in ME3 because of it.

999 and its sequel Virtue's Last Reward were also wonderful first-time runs. Skyrim too, maybe?
 
I'm going to have to say Limbo. I basically played through that game in one sitting (took me the better part of a day thanks to all the deaths), and I just loved every moment of it. The atmosphere of that game was fantastic, and the art style was just so beautiful. I still love playing through it now, but there's just so many wonderful things that you can only truly experience in your first playthrough.

Besides that, I'd have to say the Portal games.
 
Pokemon hand held series. That sense of adventure and going into the unkown... Ahh... It's a feeling that can never be re-done again.
 
There are a lot of them!

I would love the chance to play through The Last of Us for the first time, again. I got so deeply involved with the story and the characters. It was a true joy to play through. A somewhat stressful joy, as clickers freaked me out and I disliked watching the characters I'd grown attached to get mauled every time I messed up, but a joy nonetheless.

Pok?mon sapphire is another one. I'm thrilled to say that I actually do get to play this one again for the first time, sort of. Before Sapphire I was pretty young, and I'm not sure I appreciated Gen 1 and 2 like I could have (although I fired up my pokemon blue the other day and was pleasantly surprised to see my team was actually fairly balanced and high-leveled). Every gen afterward I've known quite a bit about the game before getting to play, and I usually even had a team pre-planned. My first play through Sapphire I went in only knowing the base forms of the starters. I actually got to explore the whole region of Hoenn, and I just made up my team of pokemon I liked as I went, rather than searching out those that I didn't particularly care for but had better competitive potential.

Tales of Symphonia is another one. Like the Last of Us, I became deeply involved in the characters and story. The game was HUGE to me (2 discs at the time), and it felt like I could just play and enjoy the story forever. That's kind of true, since I still really enjoy the story, but I was totally captivated that first play through.

Those are the top 3, but I could probably go on forever.
 
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Crisis Core, and the Last of Us, for their stories. I've tried replaying them, but it's just not the same already knowing how it goes.
 
Mario 64, Rayman 2, Fallout 3, Animal Crossing in general, Pokemon Red, the list goes on. It's hard to get that "aaahhhhHHHHHH!!!" feeling you get from never having experienced anything like them before.
 
Most of the Harvest Moon series, because I was thrilled to death my first play through of all of them, and now when I play them I'm kinda
"...Eh."
 
Ah I forgot Harvest Moon. I agree with that, although I still can have fun with my first HM game, Harvest Moon GB. I also am enjoying A New Beginning for 3DS, but it's the first since GameCube era that I've enjoyed one like the 3DS one
 
If I could play one game for the first time again it would be the Mass Effect Trilogy. The twists, the story, the characters, the romance...everything was magical.

Fire Emblem: Radiant Dawn is the only other game that's captured the feels the way Mass Effect did. I would choose one of those games again without a doubt.
 
Amnesia The Dark Descent, it's so overplayed by everyone on Youtube now, and even though it's still got a wonderful atmosphere, it's difficult to get as involved with it, you know everything that's coming now. Same with Outlast, even though it recently came out with a good DLC. You can never get that rush of fear back. I also wish I could play Arkham City, Deus Ex Human Revolution, and The Stanley Parable for the first time again, they were so enjoyable.
 
Dark Souls.

I've played that game so many times I pretty much know what is in every chest and around every corner, but nothing will ever compare to my first playthrough. I miss that feeling of not knowing what lies ahead and having to overcome difficult bosses/areas. I miss experiencing the beautiful atmosphere of the game for the first time and getting invaded as a helpless noob. Even Dark Souls 2 didn't give me anything close to the same feeling.
 
I have to go with Animal Crossing New Leaf. I really used to love it after the release, there was so much to discover and so on, but now - not even a year after release - it's just getting boring. And no, I haven't played it all year long without any breaks. To be honest, I haven't played it daily since.. August? Hell. :(
 
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