The prime example would have to be Al. I. Just. Can't. He is disturbing to look at and I feel like he is really clingy to me. Even though I've never let him move into my island I feel that he is scheming to sneak in, somehow.
Moose for sure, but luckily I have hardly ever come across him.
I would also like Bertha and Rhonda, because I find their designs really boring and I am so sick of seeing them on island trips. Also Hopkins, because his design from behind really creeps me out.
I bet there are others but those were the few that came to mind immediately.
Rhonda is one of the blandest villagers ever! I got her early in the game and I was so excited to find a Rhino on a mystery island but omg was she boring! I ended up bringing in an amiibo villager just to get shot of her!