If you really hate your layout, have someone hold your rare items, then pick them up after you restart your town.
- - - Post Merge - - -
As far as villagers go. You could sell or give them away before you start over. Theres a lot of great villagers in the game, and it's kind of fun meeting new ones.
Like the others said, if you're attached to your items get someone trusted to hold them and reset your town. The map is definitely something you have to like when making your town.
I would def say try to sell some of those villagers first, so you can buy ones you like for your new town. Sometimes I think we all just need to start over, it can be refreshing. Good luck.