YES!
A few that come to mind:
Cobb: A green zombie pig? Ew, gross...until he charmed me and I looked him up and his name means "Professor" in Japanese.
Angus: A big brown boring bull? No Way - but he charmed me.
Clyde - A tall yellow horse? Then I realized he is blind like DareDevil in Marvel - he's a blind superhero horse with a touch of BoJack Horseman. What's not to love?
And Anicotti - two weeks ago a random StreetPass move-in inside my perfectly crafted perfect town in progress that gave me a heart attack when her plot arrived - until I realized it was in the absolute only one perfect acceptable spot for a random move-in. And then she has moved HARD CORE into befriending everyone in town. I can't not love her. She is forcing me to adore her. She IS the star!