Danganronpa is really the only series that I've been interested in (for over a year now too) that I haven't even tried. But it's high on my list now and I'll probably get it the next time it goes on sale on Steam.
I've spoiled myself on the majority of the first game, but it's been a while and I don't really remember that much except for the "important moments." The second game I've only seen the first episode of an LP for it so that will be a fresh experience, but I'm still going to play the first game before the second.