If you have Isabelle & Digby's amiibo figurines you can give them a break by getting them into the RV campsite. Isabelle then wears specs instead of (apparently) contact lenses. She does talk about having a break. Digby too, but can't remember the exact dialog.
I'm careful when I do this, (late at night, so they don't get much of a break from me), as it can be really inconvenient to lose either Town Hall functions or the HHA plaza.